Since reports about CIA-funded LSD studies came out in the 1970s, psychedelic drugs have invoked images of unethical experimentation and “mad scientists” in the public imagination. Even now, as the stigma surrounding psychedelics diminishes in the 21st century, the figure of the “mad scientist” continues to occupy a space in what Ido Hartogsohn calls the “collective set and setting,” the larger framework of cultural understandings that shape how individuals experience psychedelic drugs. Scientists and humanities scholars who study these drugs have responded to this issue by drawing boundaries between those who used psychedelics carefully and those who used them ignorantly. Yet these boundaries were not always so clear in the past. Drawing o...